Lots on discussion of agencies. One option is have someone like Pierre duPont did for Delaware right after Prohibition — a One-Person Commissioner, not a Commission. And for putting that office on the ballot, with an extremely short term.
On revenue, paraphrasing:
The state could collect substantial revenues from selling and taxing the privilege to sell and consume marijuana. https://www.law.stanford.edu/sites/default/files/publication/988796/doc/slspublic/SLS%20Marijuana%20Policy%20Practicum%20Report.pdf